TETANUS & DIPHTHERIA TOXOIDS
Adults should have received their three-part primary immunization series
of tetanus and diphtheria as a child. A booster dose (Td) is required
every 10 years. Swelling or inflammation at the injection site may occur.
POLIO VACCINE
A one time booster dose of IPV (inactivated polio vaccine) is recommended
for immunized adults who are at risk of exposure to wild-type polio viruses
because of foreign travel or who work as health care providers. Unimmunized
adults who are at risk because of travel or occupation should receive
a primary series of IPV. The polio vaccine is not routinely recommended
for adults over 18 years of age.
MEASLES, MUMPS & RUBELLA VACCINE (MMR)
Adults born before 1957 are usually considered immune but proof of immunity
may be considered necessary for health care workers. Adults born in 1957
or later need one dose of MMR vaccine if there is no proof of immunity
or documentation of a dose of MMR given on or after the 1st birthday.
Adults in high risk groups, such as health care workers, students entering
college, and international travelers may need a second dose. top
VARICELLA-ZOSTER VACCINE (CHICKENPOX)
This vaccine is recommended for adults without a prior history of chickenpox
or the immunization. A blood test can determine whether an individual
has prior immunity. If required, all adults need two doses, the second
4-8 weeks after the first. No boosters are recommended. It should be avoided
in children and teenagers receiving aspirin, and aspirin should not be
administered to children or teenagers for 6 weeks following administration.
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INFLUENZA VACCINE
The influenza vaccine is recommended for all adults who want protection
against influenza. The vaccine is highly recommended for all persons over
the age of 50, persons with frequent infections or those with chronic
health conditions. The vaccine, which is changed each year, should be
taken annually in the autumn. The optimal time is from October to mid-November.
It is also recommended for international travelers and health care providers.
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PNEUMOCOCCAL VACCINE
The pneumococcal vaccine is recommended for patients over the age of 65,
as well as patients under that age with specific diseases or conditions
indicating a greater than normal risk for pneumococcal disease. This includes
those with chronic respiratory or cardiac diseases, diabetes, immunologic
disorders, sickle-cell disease, and those who have had surgical removal
of the spleen. A booster dose after six years is currently recommended
for those patients in the high risk groups. top
HEPATITIS B VACCINE
The hepatitis B vaccine is recommended for all sexually active non-monogamous
adults, household and sexual contacts of hepatitis B carriers, users of
illicit injectable drugs, and health care and public safety workers whose
work involves exposure to human blood. The vaccine is a three-dose series,
with the second dose one month after the first and the third dose six
months after the first dose. A booster dose is not currently recommended.
For those planning a prolonged stay in areas where hepatitis B is quite
prevalent, vaccination is recommended. These areas include: sub-Saharan
Africa, the Balkans, the Middle East, China, Southeast Asia, Korea, Indonesia,
South Pacific Islands, central Brazil, Haiti, and the Dominican Republic.
If time is pressing an accelerated schedule is possible. For those exposed
either sexually or by blood products, a post exposure treatment is available
(HBIG). It should be administered within 24-48 hours. top
TRAVEL & SPECIFIC SITUATIONS
Routine immunizations, especially tetanus/diphtheria, influenza, and polio,
should be updated before international travel. Common vaccinations for
travel are listed below. Influenza is present during our summer months
in the Southern Hemisphere. top
YELLOW FEVER VACCINE
The yellow fever vaccination is recommended for persons traveling to or
living in areas where yellow fever infection occurs. A valid International
Certificate of Vaccination is a requirement for entry into certain countries
where yellow fever occurs, or for entry into certain countries if the
traveler is arriving from an area where yellow fever occurs. The certificate
is valid for 10 years, beginning 10 days after primary immunization or
immediately after revaccination. Booster doses are recommended every 10
years. top
MENINGOCOCCAL MENINGITIS VACCINE
The meningococcal meningitis vaccination is recommended for travelers
who visit areas recognized as having epidemic meningococcal disease. It
is required for pilgrims to Mecca, Saudia Arabia for the annual Hajj.
Because of the increased incidence in dormitory living, many colleges
suggest that the meningococcal vaccine be considered. The single vaccination
provides protection for 3 years. top
TYPHOID VACCINE
The typhoid vaccine is recommended for travelers to areas where there
is a recognized risk of exposure to Salmonella typhi, the organism that
causes typhoid fever. It is transmitted by contaminated food and water.
An oral and an injectable vaccine are available. The oral typhoid vaccine
consists of 4 doses taken at two day intervals. It needs to be refrigerated
to retain full potency. The Typhoid Vi vaccine is a single injection.
Both vaccines have a low incidence of side effects. The oral vaccine must
not be given to people with decreased immunity. A Booster of the injectable
is recommended every two years. A Booster of the oral is recommended every
five years. top
HEPATITIS A VACCINE
The hepatitis A vaccine is recommended for travelers going to countries
with a high prevalence of Hepatitis A, such as those located in Central
or South America, the Caribbean, Mexico, Asia, Africa and Southern or
Eastern Europe. A second dose is given 6-12 months after the first dose.
The vaccine offers full protection two weeks after the first dose for
approximately one year. A Booster dose is not currently recommended. top
TWINRIX
The Twinrix vaccine is a combination of Hepatitis A + Hepatitis B. It
is a three dose series with a second dose one month after the first and
the third six months after the first dose. A Booster dose is not currently
recommended. top
RABIES
In many areas of the world rabies is still common. Transmission usually
occurs through the bite of a carnivorous animal. Rarely infection results
from contamination with saliva. Recently, in the United States and elsewhere,
bat bites or exposure to bat infested caves have transmitted the disease.
For those anticipating animal exposure in areas known to have rabies the
vaccine should be considered. After any exposure that might cause rabies,
an immediate post-exposure treatment series is required. top
MALARIA
Malaria is caused by an infection transmitted by the Anopheles mosquito.
It occurs predominantly in tropical and subtropical regions of Africa,
Asia, Central and South America, and Oceania. Some countries with both
urban and rural malaria may not have any malaria in major cities most
frequently visited by tourists. Most malaria is now resistant to the older
medication, chloroquine (Aralen), but generally sensitive to mefloquine
(Lariam) and atovaquone/proguanil (Malarone). Lariam is given once a week
beginning one week prior to arrival and continuing for four weeks after
departure. Lariam cannot be used in those with a history of serious psychiatric
illness or epilepsy. It also cannot be used with certain medications.
Malarone is taken daily beginning two days prior to entry into the risk
area and continuing for seven days after departure from the risk area.
Malarone should not be taken in conjunction with tetracycline, reglan,
or rifampin. All travelers to countries with malaria should seek prompt
attention for fever while traveling and for up to three years after return.
Lariam resistance is common at the Thai-Cambodian and Thai-Myanmar borders
and in Western Cambodia. For these areas Malarone or Doxycycline can be
taken. Doxycycline can cause a reaction in the sun and therefore sun block
is important, as well as protective clothing. The major human defense
against malaria is avoiding exposure to mosquitoes. This includes sleeping
inside screened areas, wearing clothing that covers the arms and legs,
avoiding outdoor activities in the evening when the mosquitoes are most
active. and using mosquito repellent. The most effective repellents contain
DEET. A long-acting formulation is Ultrathon. Other recommended available
insect repellents are Deet-Plus, Repel and Deep Woods Off. High concentrations
of DEET may cause severe skin rash, and are not recommended for children
or pregnant women. Insecticides containing permethrin may be sprayed in
living or sleeping areas at night and use of mosquito nets impregnated
with permethrin will further improve protection from malaria. top
HPV (Gardasil)
HPV (Gardasil) is a vaccine that helps protect young women against some
diseases caused by the human papillomavirus, including cervical cancer.
HPV is recommended for girls and women 9 through 26 years of age. The
schedule is three doses at intervals of 0, 2 and 6 months.top
ZOSTAVAX (Shingles)
Zostavax (Shingles) vaccine is recommended for adults 60 years of age
and older with a history of chicken pox. It is a single dose live vaccine
which substantially reduces the risk of developing shingles. It is not
indicated for those who are immunocompromised, or for those with a history
of shingles. It is not a treatment for shingles. Complete information
on Zostavax can be found here.
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TRAVELER'S DIARRHEA
In areas with poor hygiene, it is important to avoid foods that have not
been personally peeled, and tap water, including ice. This is, of course,
very difficult and, in spite of all efforts, bacterial infections causing
diarrhea are common. Lomotil or Imodium are an effective treatment for
most diarrhea. Ciprofloxacin (Cipro) 500 mg, in a single dose is often
used to treat the infection in adults. If the diarrhea is severe or associated
with a fever or bloody stools, ciprofloxacin (500 mg twice a day for seven
days) is recommended. Adequate fluid replacement is mandatory. Bismuth
subsalicylate (Pepto-Bismol) can also prevent diarrhea in travelers who
take two tablets four times daily. top
ALTITUDE ILLNESS
Altitude illness is characterized by headache, shortness of breath, and
light-headedness. Risk factors would include: fast ascent (greater than
3,000 feet per day), altitude greater than 6,000 feet, strenuous activity
at high altitude, and a previous history of altitude illness. The best
prevention of altitude illness is a slow ascent. Overexertion during the
first few days and excess dietary salt should be avoided. Acetazolamide
(Diamox) is often effective in preventing altitude illness. It is usually
taken at a dose of 500 mg per day, beginning 1-2 days before ascent and
continuing daily until 2 days after reaching maximum altitude. Altitude
illness can occasionally be very severe and may require prompt medical
attention. Acetazolamide should not be used by those who are allergic
to sulfa drugs or those with liver or kidney disease. top